Basically, each user can view the portal in their selected language and time zone. This means that when an instructor creates an ILT they will create it in their time zone.
The learners will then view the correct time of the ILT based on their selected time zone as well. So if I create an ILT for 18:00 in my own time, the learner will see that the session starts at 20:00 for example on their selected time zone.
So, the different time zone will not affect anything in the portal. It is a matter of convenience for the users to view the events translated to their time zone.